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rop-1 RNA-binding protein RO60 [ Caenorhabditis elegans ]

Gene ID: 179425, updated on 2-Nov-2024

Summary

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Official Symbol
rop-1
Official Full Name
RNA-binding protein RO60
Primary source
WormBase:WBGene00004405
Locus tag
CELE_C12D8.11
See related
AllianceGenome:WB:WBGene00004405
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including intestine. Orthologous to human RO60 (Ro60, Y RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rop-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (10252838..10255055, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene DUF3501 family protein Neighboring gene ncRNA Neighboring gene Serine/threonine-protein kinase akt-1 Neighboring gene Nuclear Hormone Receptor family Neighboring gene Serpentine Receptor, class T Neighboring gene Synaptosomal-associated protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a short form of a Caenorhabditis elegans Y RNA homolog Cel7 RNA. Chiba T, et al. Biochem Biophys Res Commun, 2021 Jun 11. PMID 33862452
  2. The Caenorhabditis elegans rop-1 gene encodes the homologue of the human 60-kDa Ro autoantigen. Labbé JC, et al. Gene, 1995 Dec 29. PMID 8566782
  3. Assessing the function of the Ro ribonucleoprotein complex using Caenorhabditis elegans as a biological tool. Labbé JC, et al. Biochem Cell Biol, 1999. PMID 10546898
  4. Caenorhabditis elegans embryos contain only one major species of Ro RNP. Van Horn DJ, et al. RNA, 1995 May. PMID 7489501, Free PMC Article
  5. The levels of the RoRNP-associated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 protein. Labbé JC, et al. Genetics, 1999 Jan. PMID 9872955, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA-binding protein RO60
NP_505638.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10252838..10255055 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073237.9 → NP_505638.1  RNA-binding protein RO60 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505638.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17933, Q27274
    Conserved Domains (1) summary
    pfam05731
    Location:63 → 473
    TROVE; TROVE domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27274.1

Gene LinkOut

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