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nol-56 Nucleolar protein 56 [ Caenorhabditis elegans ]

Gene ID: 179442, updated on 2-Nov-2024

Summary

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Official Symbol
nol-56
Official Full Name
Nucleolar protein 56
Primary source
WormBase:WBGene00010627
Locus tag
CELE_K07C5.4
See related
AllianceGenome:WB:WBGene00010627
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 36. Orthologous to human NOP56 (NOP56 ribonucleoprotein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nol-56 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (10350466..10352978, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Pre-mRNA-splicing factor SLU7 Neighboring gene Epoxide hydrolase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins. Aftab MN, et al. BMC Genomics, 2008 Jun 11. PMID 18547420, Free PMC Article
  2. The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging. Sheaffer KL, et al. Curr Biol, 2008 Sep 23. PMID 18804378, Free PMC Article
  3. Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans. Komura T, et al. NPJ Aging Mech Dis, 2021 Jun 7. PMID 34099724, Free PMC Article
  4. A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans. Xu T, et al. PLoS Genet, 2023 Feb. PMID 36763670, Free PMC Article
  5. Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. Hayes GD, et al. Cold Spring Harb Symp Quant Biol, 2006. PMID 17381276

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables snoRNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of box C/D methylation guide snoRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of box C/D methylation guide snoRNP complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nucleolar protein 56
NP_505660.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10350466..10352978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073259.11 → NP_505660.1  Nucleolar protein 56 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505660.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21276
    Conserved Domains (3) summary
    smart00931
    Location:171 → 220
    NOSIC; NOSIC (NUC001) domain
    pfam01798
    Location:177 → 412
    Nop; snoRNA binding domain, fibrillarin
    pfam08156
    Location:7 → 72
    NOP5NT; NOP5NT (NUC127) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q21276.1

Gene LinkOut

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