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pigt-1 Phosphatidylinositol glycan, class T [ Caenorhabditis elegans ]

Gene ID: 179519, updated on 2-Nov-2024

Summary

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Official Symbol
pigt-1
Official Full Name
Phosphatidylinositol glycan, class T
Primary source
WormBase:WBGene00008918
Locus tag
CELE_F17C11.7
See related
AllianceGenome:WB:WBGene00008918
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 3 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGT (phosphatidylinositol glycan anchor biosynthesis class T). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pigt-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (10956999..10958821, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene OB domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene Polysacc_synt_C domain-containing protein Neighboring gene PGG domain-containing protein Neighboring gene Vacuolar protein-sorting-associated protein 36 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in attachment of GPI anchor to protein IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in attachment of GPI anchor to protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of GPI-anchor transamidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GPI-anchor transamidase complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Phosphatidylinositol glycan, class T
NP_001023812.1
  • Confirmed by transcript evidence
NP_001023813.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10956999..10958821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028642.4 → NP_001023813.1  Phosphatidylinositol glycan, class T [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023813.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5WRN6
    Conserved Domains (1) summary
    pfam04113
    Location:18 → 452
    Gpi16; Gpi16 subunit, GPI transamidase component

  2. NM_001028641.6 → NP_001023812.1  Phosphatidylinositol glycan, class T [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023812.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19518
    Conserved Domains (1) summary
    pfam04113
    Location:18 → 468
    Gpi16; Gpi16 subunit, GPI transamidase component
Nucleotide Protein
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