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cyp-29A2 Cytochrome P450 [ Caenorhabditis elegans ]

Gene ID: 179550, updated on 2-Nov-2024

Summary

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Official Symbol
cyp-29A2
Official Full Name
Cytochrome P450
Primary source
WormBase:WBGene00011830
Locus tag
CELE_T19B10.1
See related
AllianceGenome:WB:WBGene00011830
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. Is expressed in body wall musculature; hypodermis; intestine; nervous system; and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cyp-29A2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (11217583..11219911)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Maelstrom domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein Neighboring gene Beta-galactosidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytochrome P450-dependent metabolism of eicosapentaenoic acid in the nematode Caenorhabditis elegans. Kulas J, et al. Arch Biochem Biophys, 2008 Apr 1. PMID 18282462
  2. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. Menzel R, et al. J Mol Biol, 2007 Jun 29. PMID 17499272
  3. SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension. Gao K, et al. Elife, 2019 Jan 15. PMID 30642431, Free PMC Article
  4. Eicosapentaenoic acid influences the pathogenesis of Candida albicans in Caenorhabditis elegans via inhibition of hyphal formation and stimulation of the host immune response. Mokoena NZ, et al. Med Microbiol Immunol, 2023 Oct. PMID 37672050, Free PMC Article
  5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cytochrome P450
NP_505847.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11217583..11219911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073446.5 → NP_505847.1  Cytochrome P450 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505847.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC97
    Conserved Domains (1) summary
    pfam00067
    Location:37 → 495
    p450; Cytochrome P450
Nucleotide Protein
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