U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dhs-19 DeHydrogenases, Short chain [ Caenorhabditis elegans ]

Gene ID: 179578, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
dhs-19
Official Full Name
DeHydrogenases, Short chain
Primary source
WormBase:WBGene00000982
Locus tag
CELE_T11F9.11
See related
AllianceGenome:WB:WBGene00000982
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be located in membrane. Predicted to be active in lipid droplet. Is expressed in body wall musculature; hypodermis; intestine; and pharynx. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See dhs-19 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (11489050..11490328, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene CX domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hydroxysteroid dehydrogenase family proteins on lipid droplets through bacteria, C. elegans, and mammals. Liu Y, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2018 Aug. PMID 29702244
  2. Bacterial diet modulates tamoxifen-induced death via host fatty acid metabolism. Diot C, et al. Nat Commun, 2022 Sep 23. PMID 36151093, Free PMC Article
  3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
DeHydrogenases, Short chain
NP_505915.1
  • Product from WormBase gene class dhs;
    Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11489050..11490328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073514.8 → NP_505915.1  DeHydrogenases, Short chain [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505915.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22392
    Conserved Domains (2) summary
    cd05339
    Location:42 → 282
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    pfam00106
    Location:40 → 237
    adh_short; short chain dehydrogenase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous