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usip-1 U6 snRNA-specific terminal uridylyltransferase [ Caenorhabditis elegans ]

Gene ID: 179670, updated on 2-Nov-2024

Summary

Official Symbol
usip-1
Official Full Name
U6 snRNA-specific terminal uridylyltransferase
Primary source
WormBase:WBGene00014124
Locus tag
CELE_ZK863.4
See related
AllianceGenome:WB:WBGene00014124
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables RNA uridylyltransferase activity. Involved in U6 snRNA 3'-end processing. Located in nucleoplasm. Human ortholog(s) of this gene implicated in spastic ataxia 4. Orthologous to human MTPAP (mitochondrial poly(A) polymerase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See usip-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
10
Sequence:
Chromosome: V; NC_003283.11 (12181501..12184194, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene Elongator complex protein 3 Neighboring gene G protein-coupled receptor Neighboring gene UPAR/Ly6 domain-containing protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA uridylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA uridylyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA uridylyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA 3' uridylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in U6 snRNA 3'-end processing IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
U6 snRNA-specific terminal uridylyltransferase
NP_506056.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12181501..12184194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073655.9NP_506056.1  U6 snRNA-specific terminal uridylyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506056.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23652
    Conserved Domains (2) summary
    pfam03828
    Location:382437
    PAP_assoc; Cid1 family poly A polymerase
    cl11966
    Location:142297
    NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins