U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

inx-11 Innexin;Innexin-11 [ Caenorhabditis elegans ]

Gene ID: 179710, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
inx-11
Official Full Name
Innexin;Innexin-11
Primary source
WormBase:WBGene00002133
Locus tag
CELE_W04D2.3
See related
AllianceGenome:WB:WBGene00002133
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in gap junction. Is expressed in several structures, including egg-laying apparatus; epithelial cell; pharynx; spermatid; and tail neurons. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See inx-11 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (12487234..12493269)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Alpha-actinin, sarcomeric Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class T Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ribosomal protein S11 Neighboring gene C2H2-type domain-containing protein Neighboring gene PWI domain-containing protein;RRM domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Innexins in C. elegans. Starich T, et al. Cell Commun Adhes, 2001. PMID 12064609
  2. Six innexins contribute to electrical coupling of C. elegans body-wall muscle. Liu P, et al. PLoS One, 2013. PMID 24130800, Free PMC Article
  3. Presynaptic coupling by electrical synapses coordinates a rhythmic behavior by synchronizing the activities of a neuron pair. Choi U, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972428, Free PMC Article
  4. The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. Barnes TM, et al. J Neurochem, 1997 Dec. PMID 9375655
  5. The role of gap junctions in Caenorhabditis elegans oocyte maturation and fertilization. Whitten SJ, et al. Dev Biol, 2007 Jan 15. PMID 16982048

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gap junction channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables gap junction hemi-channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in gap junction ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Innexin;Innexin-11
NP_001256426.1
  • Confirmed by transcript evidence
NP_001359736.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12487234..12493269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373129.3 → NP_001359736.1  Innexin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    C9IY29, T2DL39, T2DLM4
    Conserved Domains (1) summary
    pfam00876
    Location:20 → 383
    Innexin

  2. NM_001269497.3 → NP_001256426.1  Innexin-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256426.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23157
    UniProtKB/TrEMBL
    T2DL39
    Conserved Domains (1) summary
    pfam00876
    Location:20 → 385
    Innexin; Innexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q23157.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools