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ugt-4 UDP-glucuronosyltransferase [ Caenorhabditis elegans ]

Gene ID: 179754, updated on 2-Nov-2024

Summary

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Official Symbol
ugt-4
Official Full Name
UDP-glucuronosyltransferase
Primary source
WormBase:WBGene00013905
Locus tag
CELE_ZC455.5
See related
AllianceGenome:WB:WBGene00013905
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ugt-4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (12793014..12795336, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene Glucuronosyltransferase;UDP-glucuronosyltransferase Neighboring gene UDP-glucuronosyltransferase Neighboring gene glucuronosyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A systems biology analysis of reproductive toxicity effects induced by multigenerational exposure to ionizing radiation in C. elegans. Guédon R, et al. Ecotoxicol Environ Saf, 2021 Dec 1. PMID 34544019
  2. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-glucuronosyltransferase
NP_001041203.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12793014..12795336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047738.3 → NP_001041203.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041203.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23335
    Conserved Domains (2) summary
    PHA03392
    Location:1 → 473
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:21 → 500
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RNA

  1. NR_003178.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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