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R186.3 Signal recognition particle receptor subunit beta [ Caenorhabditis elegans ]

Gene ID: 179781, updated on 2-Nov-2024

Summary

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Official Symbol
R186.3
Official Full Name
Signal recognition particle receptor subunit beta
Primary source
WormBase:WBGene00011306
Locus tag
CELE_R186.3
See related
AllianceGenome:WB:WBGene00011306
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human SRPRB (SRP receptor subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See R186.3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (12966003..12967210, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transport and Golgi organization protein 2 homolog Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein;Serpentine Receptor, class D (delta) Neighboring gene 39S ribosomal protein L33, mitochondrial Neighboring gene MoeA N-terminal and linker domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Homodimerization of the G protein SRbeta in the nucleotide-free state involves proline cis/trans isomerization in the switch II region. Schwartz TU, et al. Proc Natl Acad Sci U S A, 2006 May 2. PMID 16627619, Free PMC Article
  2. COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells. Osterli E, et al. Genetics, 2024 May 7. PMID 38427913,
  3. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Signal recognition particle receptor subunit beta
NP_506245.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12966003..12967210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073844.8 → NP_506245.1  Signal recognition particle receptor subunit beta [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506245.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22013
    Conserved Domains (2) summary
    cd04105
    Location:39 → 234
    SR_beta; Signal recognition particle receptor, beta subunit (SR-beta), together with SR-alpha, forms the heterodimeric signal recognition particle (SRP)
    pfam09439
    Location:36 → 215
    SRPRB; Signal recognition particle receptor beta subunit
Nucleotide Protein
Heading Accession and Version

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