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pnn-1 Pinin/SDK/MemA protein domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179783, updated on 2-Nov-2024

Summary

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Official Symbol
pnn-1
Official Full Name
Pinin/SDK/MemA protein domain-containing protein
Primary source
WormBase:WBGene00011308
Locus tag
CELE_R186.7
See related
AllianceGenome:WB:WBGene00011308
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PNN (pinin, desmosome associated protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pnn-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (12971110..12973281)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 39S ribosomal protein L33, mitochondrial Neighboring gene MoeA N-terminal and linker domain-containing protein Neighboring gene BTB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pinin/SDK/MemA protein domain-containing protein
NP_506247.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12971110..12973281
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073846.6 → NP_506247.1  Pinin/SDK/MemA protein domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506247.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95ZQ5
    Conserved Domains (2) summary
    pfam04696
    Location:154 → 273
    Pinin_SDK_memA; pinin/SDK/memA/ protein conserved region
    pfam04697
    Location:6 → 146
    Pinin_SDK_N; pinin/SDK conserved region
Nucleotide Protein
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