U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nasp-2 Tetratricopeptide SHNi-TPR domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179810, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
nasp-2
Official Full Name
Tetratricopeptide SHNi-TPR domain-containing protein
Primary source
WormBase:WBGene00008218
Locus tag
CELE_C50B6.2
See related
AllianceGenome:WB:WBGene00008218
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable histone binding activity. Predicted to be involved in CENP-A containing chromatin assembly and DNA replication-dependent chromatin assembly. Predicted to be active in nucleoplasm. Is expressed in germ line; intestine; and nervous system. Orthologous to human NASP (nuclear autoantigenic sperm protein). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See nasp-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (13310186..13312260, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Homeobox domain-containing protein;Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene DUF4817 domain-containing protein Neighboring gene DUF3452 domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. C. elegans feed yolk to their young in a form of primitive lactation. Kern CC, et al. Nat Commun, 2021 Oct 5. PMID 34611154, Free PMC Article
  2. In vivo and transcriptome-wide identification of RNA binding protein target sites. Jungkamp AC, et al. Mol Cell, 2011 Dec 9. PMID 22152485, Free PMC Article
  3. The PLZF-like protein TRA-4 cooperates with the Gli-like transcription factor TRA-1 to promote female development in C. elegans. Grote P, et al. Dev Cell, 2006 Oct. PMID 17011494
  4. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
  5. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA replication-dependent chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Tetratricopeptide SHNi-TPR domain-containing protein
NP_506298.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13310186..13312260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073897.8 → NP_506298.1  Tetratricopeptide SHNi-TPR domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506298.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17687
    Conserved Domains (2) summary
    pfam13424
    Location:376 → 453
    TPR_12; Tetratricopeptide repeat
    pfam10516
    Location:379 → 416
    SHNi-TPR
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools