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somi-1 Zinc finger protein somi-1 [ Caenorhabditis elegans ]

Gene ID: 179819, updated on 2-Nov-2024

Summary

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Official Symbol
somi-1
Official Full Name
Zinc finger protein somi-1
Primary source
WormBase:WBGene00010868
Locus tag
CELE_M04G12.4
See related
AllianceGenome:WB:WBGene00010868
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in cell differentiation. Located in nucleus. Is expressed in several structures, including gonad; hypodermal cell; intestine; neurons; and vulval precursor cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See somi-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (13386058..13391395, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene IRF-2BP1_2 domain-containing protein;Interferon regulatory factor 2-binding protein 1 & 2 zinc finger domain-containing protein;RING-type domain-containing protein Neighboring gene cathepsin X Neighboring gene Soluble guanylate cyclase gcy-34 Neighboring gene ncRNA Neighboring gene ZP domain-containing protein Neighboring gene ncRNA Neighboring gene NADP-dependent oxidoreductase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA. Hayes GD, et al. Genes Dev, 2011 Oct 1. PMID 21979920, Free PMC Article
  2. Caenorhabditis elegans SET1/COMPASS Maintains Germline Identity by Preventing Transcriptional Deregulation Across Generations. Robert VJ, et al. Front Cell Dev Biol, 2020. PMID 33072747, Free PMC Article
  3. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. somi-1 coordinates a nuclear response that complements the activity of mir-84
    Title: The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zinc finger protein somi-1
NP_001360520.1
  • Confirmed by transcript evidence
NP_001360558.1
  • Confirmed by transcript evidence
NP_001379322.1
  • Confirmed by transcript evidence
NP_506320.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13386058..13391395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073919.6 → NP_506320.3  Zinc finger protein somi-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506320.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBR5
    Conserved Domains (1) summary
    pfam13909
    Location:454 → 478
    zf-H2C2_5; C2H2-type zinc-finger domain

  2. NM_001373144.3 → NP_001360520.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A486WWJ9, A0A486WWS8, G5EBR5, Q8I4H1
    Conserved Domains (1) summary
    pfam13909
    Location:454 → 473
    zf-H2C2_5; C2H2-type zinc-finger domain

  3. NM_001392639.1 → NP_001379322.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam13909
    Location:425 → 444
    zf-H2C2_5; C2H2-type zinc-finger domain

  4. NM_001373145.2 → NP_001360558.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam13909
    Location:425 → 444
    zf-H2C2_5; C2H2-type zinc-finger domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A486WWJ9.1

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