U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cest-1.2 Carboxylic ester hydrolase [ Caenorhabditis elegans ]

Gene ID: 179914, updated on 2-Nov-2024

Summary

Official Symbol
cest-1.2
Official Full Name
Carboxylic ester hydrolase
Primary source
WormBase:WBGene00011364
Locus tag
CELE_T02B5.3
See related
AllianceGenome:WB:WBGene00011364
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See cest-1.2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (14157663..14160862, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene Serpentine receptor class delta-26 Neighboring gene Carboxylic ester hydrolase

General protein information

Preferred Names
Carboxylic ester hydrolase
NP_506504.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14157663..14160862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074103.7NP_506504.2  Carboxylic ester hydrolase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506504.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    P92016
    Conserved Domains (2) summary
    COG0657
    Location:125250
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    pfam00135
    Location:21536
    COesterase; Carboxylesterase family