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cept-2 Choline/EthanolaminePhosphoTransferase [ Caenorhabditis elegans ]

Gene ID: 179935, updated on 2-Nov-2024

Summary

Official Symbol
cept-2
Official Full Name
Choline/EthanolaminePhosphoTransferase
Primary source
WormBase:WBGene00013024
Locus tag
CELE_Y49A3A.1
See related
AllianceGenome:WB:WBGene00013024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable diacylglycerol cholinephosphotransferase activity and ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Orthologous to several human genes including CHPT1 (choline phosphotransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See cept-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (14347766..14351482)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene V-type proton ATPase catalytic subunit A Neighboring gene tRNA:m(4)X modification enzyme TRM13 Neighboring gene Peptidyl-prolyl cis-trans isomerase 1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables diacylglycerol cholinephosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ethanolaminephosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphotransferase activity, for other substituted phosphate groups IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in CDP-choline pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Choline/EthanolaminePhosphoTransferase
NP_506558.2
  • Product from WormBase gene class cept;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14347766..14351482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074157.7NP_506558.2  Choline/EthanolaminePhosphoTransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506558.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC25
    Conserved Domains (1) summary
    cl00453
    Location:53421
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase