U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mut-15 MUTator [ Caenorhabditis elegans ]

Gene ID: 180000, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
mut-15
Official Full Name
MUTator
Primary source
WormBase:WBGene00011323
Locus tag
CELE_T01C3.8
See related
AllianceGenome:WB:WBGene00011323
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in mutator focus. Is expressed in germ line. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See mut-15 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (15002543..15005067)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Spore coat protein;Transmembrane protein Neighboring gene Small ribosomal subunit protein uS9 Neighboring gene rRNA 2'-O-methyltransferase fibrillarin Neighboring gene Protein hrde-2 Neighboring gene Ionotropic glutamate receptor C-terminal domain-containing protein;PBPe domain-containing protein Neighboring gene Oxysterol binding protein;Oxysterol-binding protein Neighboring gene ncRNA Neighboring gene tRNA-Val

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline. Phillips CM, et al. Genes Dev, 2012 Jul 1. PMID 22713602, Free PMC Article
  2. Disruption of the mutator complex triggers a low penetrance larval arrest phenotype. Rogers AK, et al. MicroPubl Biol, 2020. PMID 32542232, Free PMC Article
  3. A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi. Tsai HY, et al. Cell, 2015 Jan 29. PMID 25635455, Free PMC Article
  4. Distinct regions of the intrinsically disordered protein MUT-16 mediate assembly of a small RNA amplification complex and promote phase separation of Mutator foci. Uebel CJ, et al. PLoS Genet, 2018 Jul. PMID 30036386, Free PMC Article
  5. MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation. Phillips CM, et al. Curr Biol, 2014 Apr 14. PMID 24684932, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in mutator focus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
MUTator
NP_001256638.1
  • Product from WormBase gene class mut;
    Confirmed by transcript evidence
NP_001256639.1
  • Product from WormBase gene class mut;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    15002543..15005067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269709.2 → NP_001256638.1  MUTator [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256638.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22061

  2. NM_001269710.3 → NP_001256639.1  MUTator [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256639.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1B6U1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools