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sdc-3 Zinc finger protein sdc-3 [ Caenorhabditis elegans ]

Gene ID: 180009, updated on 2-Nov-2024

Summary

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Official Symbol
sdc-3
Official Full Name
Zinc finger protein sdc-3
Primary source
WormBase:WBGene00004747
Locus tag
CELE_C25D7.3
See related
AllianceGenome:WB:WBGene00004747
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables sequence-specific DNA binding activity. Involved in mitotic sister chromatid segregation; negative regulation of transcription by RNA polymerase II; and sex determination. Located in X chromosome and nucleus. Is expressed in germ line and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sdc-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
15
Sequence:
Chromosome: V; NC_003283.11 (15039148..15048207, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Major sperm protein Neighboring gene pseudo Neighboring gene DUF38 domain-containing protein;F-box domain-containing protein Neighboring gene Metallo-beta-lactamase domain-containing protein Neighboring gene 40S ribosomal protein S20

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans. Kim J, et al. Elife, 2022 Nov 4. PMID 36331876, Free PMC Article
  2. X chromosome repression by localization of the C. elegans dosage compensation machinery to sites of transcription initiation. Ercan S, et al. Nat Genet, 2007 Mar. PMID 17293863, Free PMC Article
  3. Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex. McDonel P, et al. Nature, 2006 Nov 30. PMID 17122774, Free PMC Article
  4. Functions of the Caenorhabditis elegans regulatory myosin light chain genes mlc-1 and mlc-2. Rushforth AM, et al. Genetics, 1998 Nov. PMID 9799259, Free PMC Article
  5. The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal-effect genes required for survival of the germline in Caenorhabditis elegans, is sensitive to chromosome dosage. Garvin C, et al. Genetics, 1998 Jan. PMID 9475730, Free PMC Article

See all (64) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic sister chromatid segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sex determination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in X chromosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zinc finger protein sdc-3
NP_506703.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    15039148..15048207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074302.4 → NP_506703.1  Zinc finger protein sdc-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506703.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17596, P34706
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34706.2

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