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F22B8.7 MOSC domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180078, updated on 2-Nov-2024

Summary

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Official Symbol
F22B8.7
Official Full Name
MOSC domain-containing protein
Primary source
WormBase:WBGene00009049
Locus tag
CELE_F22B8.7
See related
AllianceGenome:WB:WBGene00009049
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable catalytic activity; molybdenum ion binding activity; and pyridoxal phosphate binding activity. Involved in regulation of protein deneddylation. Located in cytoplasm and nucleus. Orthologous to human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F22B8.7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (16094584..16097320)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Seven TM Receptor Neighboring gene G protein-coupled receptor;Seven TM Receptor Neighboring gene cystathionine gamma-lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Using RNA interference to identify specific modifiers of a temperature-sensitive, embryonic-lethal mutation in the Caenorhabditis elegans ubiquitin-like Nedd8 protein modification pathway E1-activating gene rfl-1. Dorfman M, et al. Genetics, 2009 Aug. PMID 19528325, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables molybdenum ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of protein deneddylation IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
MOSC domain-containing protein
NP_507051.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    16094584..16097320
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074650.7 → NP_507051.2  MOSC domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507051.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45394
    Conserved Domains (2) summary
    COG3217
    Location:45 → 339
    YcbX; Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains [General function prediction only]
    pfam03476
    Location:42 → 166
    MOSC_N; MOSC N-terminal beta barrel domain
Nucleotide Protein
Heading Accession and Version

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