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ifas-2 Inducible FAScin Domain containing [ Caenorhabditis elegans ]

Gene ID: 180128, updated on 2-Nov-2024

Summary

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Official Symbol
ifas-2
Official Full Name
Inducible FAScin Domain containing
Primary source
WormBase:WBGene00008615
Locus tag
CELE_F09C6.1
See related
AllianceGenome:WB:WBGene00008615
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in cytoplasm. Predicted to be active in actin cytoskeleton. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ifas-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (16887357..16888888, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Flagellar rod assembly protein/muramidase FlgJ Neighboring gene FlxA-like protein Neighboring gene F-box domain-containing protein Neighboring gene DUF38 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ifas-1 is upregulated by fungal infection in a GPA-12 and STA-2-independent manner in the Caenorhabditis elegans epidermis. Omi S, et al. MicroPubl Biol, 2021 May 25. PMID 34056565, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Inducible FAScin Domain containing
NP_507266.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class ifas

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    16887357..16888888 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074865.5 → NP_507266.1  Inducible FAScin Domain containing [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507266.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45327
    Conserved Domains (1) summary
    cd00257
    Location:106 → 223
    Fascin; Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an ...
Nucleotide Protein
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