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nhr-65 Nuclear hormone receptor family member nhr-65 [ Caenorhabditis elegans ]

Gene ID: 180230, updated on 2-Nov-2024

Summary

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Official Symbol
nhr-65
Official Full Name
Nuclear hormone receptor family member nhr-65
Primary source
WormBase:WBGene00003655
Locus tag
CELE_Y17D7A.3
See related
AllianceGenome:WB:WBGene00003655
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including excretory cell; intestine; muscle cell; pharynx; and tail spike. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nhr-65 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (18839304..18845443)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene EF-hand domain-containing protein Neighboring gene tRNA Neighboring gene CYtochrome P450 family Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene tryptophan--tRNA ligase Neighboring gene AAA_12 domain-containing protein;DNA2/NAM7 helicase-like C-terminal domain-containing protein;Intron-binding protein aquarius Neighboring gene Homeobox protein ceh-51

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternative splicing regulation during C. elegans development: splicing factors as regulated targets. Barberan-Soler S, et al. PLoS Genet, 2008 Feb 29. PMID 18454200, Free PMC Article
  2. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Piazzesi A, et al. EMBO Rep, 2022 May 4. PMID 35297148, Free PMC Article
  3. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear hormone receptor family member nhr-65
NP_001024219.1
  • Confirmed by transcript evidence
NP_001024220.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    18839304..18845443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029049.6 → NP_001024220.1  Nuclear hormone receptor family member nhr-65 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024220.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45907
    Conserved Domains (2) summary
    pfam00104
    Location:165 → 375
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
    cl02596
    Location:13 → 75
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. NM_001029048.7 → NP_001024219.1  Nuclear hormone receptor family member nhr-65 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024219.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45907, Q7YTK0, Q9GTE3
    Conserved Domains (2) summary
    pfam00104
    Location:165 → 375
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
    cl02596
    Location:13 → 75
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O45907.1

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