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tgt-2 Queuine tRNA-ribosyltransferase accessory subunit 2 [ Caenorhabditis elegans ]

Gene ID: 180244, updated on 2-Nov-2024

Summary

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Official Symbol
tgt-2
Official Full Name
Queuine tRNA-ribosyltransferase accessory subunit 2
Primary source
WormBase:WBGene00006567
Locus tag
CELE_Y39B6A.35
See related
AllianceGenome:WB:WBGene00006567
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity and tRNA-guanosine(34) queuine transglycosylase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be located in cytoplasm. Is expressed in intestine and nervous system. Orthologous to human QTRT2 (queuine tRNA-ribosyltransferase accessory subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tgt-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (18998345..19000918)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Structural protein Neighboring gene General transcription factor IIF subunit 2 Neighboring gene APOPT family protein Y39B6A.34, mitochondrial;COA8 family protein Y39B6A.34, mitochondrial Neighboring gene Ribosome biogenesis protein NOP53

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pentosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA-guanosine(34) queuine transglycosylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA modification IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA-guanine transglycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA-guanine transglycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Queuine tRNA-ribosyltransferase accessory subunit 2
NP_741662.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    18998345..19000918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171572.4 → NP_741662.1  Queuine tRNA-ribosyltransferase accessory subunit 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741662.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9NEU3
    Conserved Domains (2) summary
    COG0343
    Location:4 → 369
    Tgt; Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]
    pfam01702
    Location:149 → 369
    TGT; Queuine tRNA-ribosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NEU3.1

Gene LinkOut

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