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F13C5.2 Bromo domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180410, updated on 2-Nov-2024

Summary

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Official Symbol
F13C5.2
Official Full Name
Bromo domain-containing protein
Primary source
WormBase:WBGene00017423
Locus tag
CELE_F13C5.2
See related
AllianceGenome:WB:WBGene00017423
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed widely. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F13C5.2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
5
Sequence:
Chromosome: X; NC_003284.9 (593960..596293)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Multidrug resistance-associated protein 1 Neighboring gene Multidrug resistance-associated protein 1 Neighboring gene Neuropeptide-Like Protein;Peptidase_M13 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lysine-acetylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Bromo domain-containing protein
NP_508124.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    593960..596293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075723.7 → NP_508124.1  Bromo domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508124.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76561
    Conserved Domains (1) summary
    cl02556
    Location:118 → 219
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
Nucleotide Protein
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