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dop-6 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180706, updated on 2-Nov-2024

Summary

Official Symbol
dop-6
Official Full Name
G-protein coupled receptors family 1 profile domain-containing protein
Primary source
WormBase:WBGene00016037
Locus tag
CELE_C24A8.1
See related
AllianceGenome:WB:WBGene00016037
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; cellular response to dopamine; and chemical synaptic transmission. Predicted to be located in membrane and synapse. Predicted to be active in dendrite and plasma membrane. Is expressed in several structures, including AVF; SMDVL; head neurons; intestine; and lumbar neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See dop-6 in Genome Data Viewer
Location:
chromosome: X
Exon count:
17
Sequence:
Chromosome: X; NC_003284.9 (4320863..4327331)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled amine receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables G protein-coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
G-protein coupled receptors family 1 profile domain-containing protein
NP_001359889.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4320863..4327331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373279.1NP_001359889.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91096
    Conserved Domains (3) summary
    cd14967
    Location:24217
    7tmA_amine_R-like; amine receptors and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    cd14964
    Location:466496
    7tm_GPCRs; TM helix 6 [structural motif]
    cl28897
    Location:464542
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily