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cest-26 Carboxylic ester hydrolase [ Caenorhabditis elegans ]

Gene ID: 180715, updated on 2-Nov-2024

Summary

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Official Symbol
cest-26
Official Full Name
Carboxylic ester hydrolase
Primary source
WormBase:WBGene00017478
Locus tag
CELE_F15A8.6
See related
AllianceGenome:WB:WBGene00017478
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cest-26 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (4430862..4437655, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene UMA domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Carboxylic ester hydrolase
NP_001367709.1
  • Confirmed by transcript evidence
NP_001368609.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4430862..4437655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380948.2 → NP_001367709.1  Carboxylic ester hydrolase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O02147
    Conserved Domains (1) summary
    pfam00135
    Location:20 → 555
    COesterase; Carboxylesterase family

  2. NM_001380947.1 → NP_001368609.1  Carboxylic ester hydrolase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1C3NSL8
    Conserved Domains (1) summary
    pfam00135
    Location:40 → 575
    COesterase; Carboxylesterase family
Nucleotide Protein
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