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T07F12.4 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180763, updated on 2-Nov-2024

Summary

Official Symbol
T07F12.4
Official Full Name
Protein kinase domain-containing protein
Primary source
WormBase:WBGene00020324
Locus tag
CELE_T07F12.4
See related
AllianceGenome:WB:WBGene00020324
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including axon extension; macroautophagy; and regulation of autophagy. Predicted to be active in autophagosome; cytosol; and phagophore assembly site membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See T07F12.4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (4896602..4900801, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene PA domain-containing protein Neighboring gene Steroid-phosphate phosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RAB6-interacting golgin;Ras-associating domain-containing protein Neighboring gene Intermediate filament protein ifa-4

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in axon extension IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in phagophore assembly site membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Protein kinase domain-containing protein
NP_001368727.1
  • Confirmed by transcript evidence
NP_001380246.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4896602..4900801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392768.1NP_001380246.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6MYF5
    Conserved Domains (1) summary
    smart00220
    Location:42292
    S_TKc; Serine/Threonine protein kinases, catalytic domain
  2. NM_001380955.1NP_001368727.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6NNZ8
    Conserved Domains (1) summary
    smart00220
    Location:66316
    S_TKc; Serine/Threonine protein kinases, catalytic domain