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dpy-8 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180785, updated on 2-Nov-2024

Summary

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Official Symbol
dpy-8
Official Full Name
Nematode cuticle collagen N-terminal domain-containing protein
Primary source
WormBase:WBGene00001070
Locus tag
CELE_C31H2.2
See related
AllianceGenome:WB:WBGene00001070
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Used to study skin disease. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dpy-8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (5148804..5150476, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Rab-GAP TBC domain-containing protein;TLDc domain-containing protein Neighboring gene ncRNA Neighboring gene Ovule protein Neighboring gene Uncharacterized protein Neighboring gene Putative protein C31H2.4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans. Politz SM, et al. Proc Natl Acad Sci U S A, 1990 Apr. PMID 1691498, Free PMC Article
  2. Identification of genes that interact with glp-1, a gene required for inductive cell interactions in Caenorhabditis elegans. Maine EM, et al. Development, 1989 May. PMID 2627884
  3. Genetics of intercellular signalling in C. elegans. Austin J, et al. Development, 1989. PMID 2699857
  4. Two sets of interacting collagens form functionally distinct substructures within a Caenorhabditis elegans extracellular matrix. McMahon L, et al. Mol Biol Cell, 2003 Apr. PMID 12686594, Free PMC Article
  5. Genetic control of cell communication in C. elegans development. Maine EM, et al. Bioessays, 1990 Jun. PMID 2201294

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nematode cuticle collagen N-terminal domain-containing protein
NP_508873.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5148804..5150476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076472.4 → NP_508873.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508873.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18345
    Conserved Domains (1) summary
    smart01088
    Location:7 → 58
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
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