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sto-2 Stomatin-2 [ Caenorhabditis elegans ]

Gene ID: 180802, updated on 2-Nov-2024

Summary

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Official Symbol
sto-2
Official Full Name
Stomatin-2
Primary source
WormBase:WBGene00006064
Locus tag
CELE_F32A6.5
See related
AllianceGenome:WB:WBGene00006064
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including STOM (stomatin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sto-2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
12
Sequence:
Chromosome: X; NC_003284.9 (5307486..5323387, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Activator of G protein signaling;TPR_REGION domain-containing protein;Tetratricopeptide repeat protein 28 Neighboring gene ncRNA Neighboring gene IFT81 calponin homology domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Serine protease K12H4.7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
  2. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950
  3. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
  4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Stomatin-2
NP_001257020.1
  • Confirmed by transcript evidence
NP_001257021.1
  • Confirmed by transcript evidence
NP_001257022.1
  • Confirmed by transcript evidence
NP_001257023.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5307486..5323387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270092.5 → NP_001257021.1  Stomatin-2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257021.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D5MCN3, D5MCN4, D5MCN5, D5MCN6, Q19958
    Conserved Domains (2) summary
    smart00244
    Location:146 → 298
    PHB; prohibitin homologues
    cl19107
    Location:168 → 368
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  2. NM_001270091.4 → NP_001257020.1  Stomatin-2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257020.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19958
    Conserved Domains (2) summary
    smart00244
    Location:129 → 281
    PHB; prohibitin homologues
    cl19107
    Location:151 → 351
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  3. NM_001270094.2 → NP_001257023.1  Stomatin-2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257023.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19958
    Conserved Domains (2) summary
    smart00244
    Location:91 → 243
    PHB; prohibitin homologues
    cl19107
    Location:113 → 313
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  4. NM_001270093.4 → NP_001257022.1  Stomatin-2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257022.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19958
    Conserved Domains (2) summary
    smart00244
    Location:118 → 270
    PHB; prohibitin homologues
    cl19107
    Location:140 → 340
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q19958.4

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