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set-19 SET domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180834, updated on 2-Nov-2024

Summary

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Official Symbol
set-19
Official Full Name
SET domain-containing protein
Primary source
WormBase:WBGene00020919
Locus tag
CELE_W01C8.3
See related
AllianceGenome:WB:WBGene00020919
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable histone H3 methyltransferase activity. Predicted to be located in chromatin. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See set-19 in Genome Data Viewer
Location:
chromosome: X
Exon count:
8
Sequence:
Chromosome: X; NC_003284.9 (5675177..5680225, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene HMG box domain-containing protein;Transcription factor egl-13 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SET domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans. Huang M, et al. Elife, 2022 Sep 20. PMID 36125117, Free PMC Article
  2. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
  3. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190
  4. Epigenetics in C. elegans: facts and challenges. Wenzel D, et al. Genesis, 2011 Aug. PMID 21538806
  5. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables histone H3 methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SET domain-containing protein
NP_001379854.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5675177..5680225 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392778.1 → NP_001379854.1  SET domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GYG8
    Conserved Domains (1) summary
    smart00317
    Location:175 → 322
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
Nucleotide Protein
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