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W01C8.5 DM13 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180836, updated on 2-Nov-2024

Summary

Official Symbol
W01C8.5
Official Full Name
DM13 domain-containing protein
Primary source
WormBase:WBGene00020921
Locus tag
CELE_W01C8.5
See related
AllianceGenome:WB:WBGene00020921
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See W01C8.5 in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (5694471..5697308, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene SET domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

General protein information

Preferred Names
DM13 domain-containing protein
NP_001123187.1
  • Confirmed by transcript evidence
NP_508959.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5694471..5697308 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129715.6NP_001123187.1  DM13 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001123187.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZL4
    Conserved Domains (1) summary
    cl02735
    Location:4076
    DM13; Electron transfer DM13
  2. NM_076558.11NP_508959.1  DM13 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508959.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBU2
    Conserved Domains (2) summary
    smart00686
    Location:38146
    DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
    cl02735
    Location:160264
    DM13; Electron transfer DM13