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R07E4.1 Fibronectin type-III domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180863, updated on 2-Nov-2024

Summary

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Official Symbol
R07E4.1
Official Full Name
Fibronectin type-III domain-containing protein
Primary source
WormBase:WBGene00019935
Locus tag
CELE_R07E4.1
See related
AllianceGenome:WB:WBGene00019935
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to be active in spindle. Orthologous to human ANKFN1 (ankyrin repeat and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See R07E4.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
23
Sequence:
Chromosome: X; NC_003284.9 (5959115..5970273)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Cytochrome b-c1 complex subunit 8 Neighboring gene ncRNA Neighboring gene cAMP-dependent protein kinase regulatory subunit Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in establishment of mitotic spindle orientation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of establishment of bipolar cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in spindle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Fibronectin type-III domain-containing protein
NP_001361971.1
  • Confirmed by transcript evidence
NP_001361972.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5959115..5970273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001375040.2 → NP_001361971.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZC1
    Conserved Domains (2) summary
    cd00063
    Location:327 → 409
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl28922
    Location:1026 → 1119
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. NM_001375041.2 → NP_001361972.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5WRT5
    Conserved Domains (2) summary
    cd00063
    Location:228 → 310
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl28922
    Location:927 → 1020
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein
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