U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

bca-1 Beta carbonic anhydrase 1 [ Caenorhabditis elegans ]

Gene ID: 180890, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
bca-1
Official Full Name
Beta carbonic anhydrase 1
Primary source
WormBase:WBGene00000245
Locus tag
CELE_T13C5.5
See related
AllianceGenome:WB:WBGene00000245
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Acts upstream of or within IRE1-mediated unfolded protein response. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See bca-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (6201875..6204746, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Homeobox domain-containing protein Neighboring gene 3-ketosteroid oxygenase;Cytochrome P450 Neighboring gene Mitochondrial fission process protein 1 Neighboring gene Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular and biochemical analysis of the beta class carbonic anhydrases in Caenorhabditis elegans. Fasseas MK, et al. Mol Biol Rep, 2010 Jul. PMID 19816790
  2. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
  3. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Beta carbonic anhydrase 1
NP_741809.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6201875..6204746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171701.7 → NP_741809.1  Beta carbonic anhydrase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741809.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22460
    Conserved Domains (1) summary
    cd00884
    Location:7 → 228
    beta_CA_cladeB; Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22460.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools