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fbxl-4 F-box domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180930, updated on 2-Nov-2024

Summary

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Official Symbol
fbxl-4
Official Full Name
F-box domain-containing protein
Primary source
WormBase:WBGene00020884
Locus tag
CELE_T28B4.1
See related
AllianceGenome:WB:WBGene00020884
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in positive regulation of protein ubiquitination. Is expressed in body wall musculature and vulval muscle. Orthologous to human FBXL17 (F-box and leucine rich repeat protein 17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fbxl-4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
12
Sequence:
Chromosome: X; NC_003284.9 (6588795..6596139)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene Transthyretin-like family protein Neighboring gene Lens fiber membrane intrinsic protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The F-box protein family. Kipreos ET, et al. Genome Biol, 2000. PMID 11178263, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in positive regulation of protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
F-box domain-containing protein
NP_001024931.1
  • Confirmed by transcript evidence
NP_509108.1
  • Confirmed by transcript evidence
NP_509109.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6588795..6596139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029760.4 → NP_001024931.1  F-box domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024931.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6A590
    Conserved Domains (3) summary
    cd09293
    Location:244 → 358
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:252 → 277
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:66 → 110
    F-box-like

  2. NM_076707.5 → NP_509108.1  F-box domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509108.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZV3
    Conserved Domains (3) summary
    cd09293
    Location:210 → 324
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:218 → 243
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:32 → 76
    F-box-like

  3. NM_076708.4 → NP_509109.1  F-box domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509109.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZV2
    Conserved Domains (3) summary
    cd09293
    Location:227 → 341
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:235 → 260
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:49 → 93
    F-box-like
Nucleotide Protein
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