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clec-266 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180932, updated on 2-Nov-2024

Summary

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Official Symbol
clec-266
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00016088
Locus tag
CELE_C25B8.4
See related
AllianceGenome:WB:WBGene00016088
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in intestinal cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clec-266 in Genome Data Viewer
Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (6617393..6622915, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Cathepsin B-like cysteine proteinase 6 Neighboring gene Claudin domain-containing protein 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Potassium voltage-gated channel subfamily KQT member 5 Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Schulenburg H, et al. Immunobiology, 2008. PMID 18406370
  2. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  3. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  4. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
  5. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
C-type lectin domain-containing protein
NP_001024427.1
  • Confirmed by transcript evidence
NP_001024428.1
  • Confirmed by transcript evidence
NP_001379719.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6617393..6622915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029256.4 → NP_001024427.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024427.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZ06
    Conserved Domains (1) summary
    smart00034
    Location:58 → 195
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)

  2. NM_001392791.1 → NP_001379719.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7Z121
    Conserved Domains (1) summary
    smart00034
    Location:58 → 121
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)

  3. NM_001029257.5 → NP_001024428.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024428.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZ07
    Conserved Domains (1) summary
    smart00034
    Location:94 → 231
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
Nucleotide Protein
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