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inx-1 Innexin [ Caenorhabditis elegans ]

Gene ID: 180968, updated on 2-Nov-2024

Summary

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Official Symbol
inx-1
Official Full Name
Innexin
Primary source
WormBase:WBGene00002123
Locus tag
CELE_C16E9.4
See related
AllianceGenome:WB:WBGene00002123
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in gap junction. Is expressed in neurons and pm1. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See inx-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Sequence:
Chromosome: X; NC_003284.9 (6943735..6956399, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene DUF2045 domain containing protein;Transposase Neighboring gene ncRNA Neighboring gene VWFA domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses. Hori S, et al. PLoS Genet, 2018 Jun. PMID 29939997, Free PMC Article
  2. C. elegans enteric motor neurons fire synchronized action potentials underlying the defecation motor program. Jiang J, et al. Nat Commun, 2022 May 19. PMID 35589790, Free PMC Article
  3. Innexins in C. elegans. Starich T, et al. Cell Commun Adhes, 2001. PMID 12064609
  4. Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system. Starich TA, et al. Neural Dev, 2009 May 11. PMID 19432959, Free PMC Article
  5. Six innexins contribute to electrical coupling of C. elegans body-wall muscle. Liu P, et al. PLoS One, 2013. PMID 24130800, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Innexin
NP_001024407.1
  • Confirmed by transcript evidence
NP_741826.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6943735..6956399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171716.5 → NP_741826.1  Innexin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741826.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17394, T2DKY3
    Conserved Domains (1) summary
    pfam00876
    Location:19 → 366
    Innexin; Innexin

  2. NM_001029236.3 → NP_001024407.1  Innexin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024407.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG52, T2DKY3
    Conserved Domains (1) summary
    pfam00876
    Location:19 → 366
    Innexin; Innexin

RNA

  1. NR_131721.1 RNA Sequence

    Status: REVIEWED

  2. NR_131724.1 RNA Sequence

    Status: REVIEWED

  3. NR_131723.1 RNA Sequence

    Status: REVIEWED

  4. NR_131722.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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