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F26A10.2 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181025, updated on 2-Nov-2024

Summary

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Official Symbol
F26A10.2
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00017814
Locus tag
CELE_F26A10.2
See related
AllianceGenome:WB:WBGene00017814
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 22 and lethal congenital contracture syndrome. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18); ZBTB42 (zinc finger and BTB domain containing 42); and ZNF148 (zinc finger protein 148). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F26A10.2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
9
Sequence:
Chromosome: X; NC_003284.9 (7630526..7637172, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An actin-based viscoplastic lock ensures progressive body-axis elongation. Lardennois A, et al. Nature, 2019 Sep. PMID 31462781, Free PMC Article
  2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
  3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chromatin insulator sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in chromosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C2H2-type domain-containing protein
NP_509290.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    7630526..7637172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076889.5 → NP_509290.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509290.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19807
    Conserved Domains (2) summary
    sd00017
    Location:50 → 70
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:272 → 348
    zf-C2H2_8; C2H2-type zinc ribbon
Nucleotide Protein
Heading Accession and Version

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