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zig-12 Ig-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181123, updated on 2-Nov-2024

Summary

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Official Symbol
zig-12
Official Full Name
Ig-like domain-containing protein
Primary source
WormBase:WBGene00019727
Locus tag
CELE_M02D8.1
See related
AllianceGenome:WB:WBGene00019727
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in axon guidance. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is expressed in body wall musculature and vulval muscle. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See zig-12 in Genome Data Viewer
Location:
chromosome: X
Exon count:
5
Sequence:
Chromosome: X; NC_003284.9 (8763907..8766280)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CUB_2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans. Lesanpezeshki L, et al. Sci Rep, 2019 Oct 23. PMID 31645584, Free PMC Article
  2. An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. Budovskaya YV, et al. Cell, 2008 Jul 25. PMID 18662544, Free PMC Article
  3. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in sarcomere HDA PubMed 
located_in striated muscle dense body HDA PubMed 

General protein information

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Preferred Names
Ig-like domain-containing protein
NP_509485.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    8763907..8766280
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077084.7 → NP_509485.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509485.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21465
    Conserved Domains (2) summary
    PHA03273
    Location:39 → 143
    PHA03273; envelope glycoprotein C; Provisional
    cl11960
    Location:100 → 194
    Ig; Immunoglobulin domain
Nucleotide Protein
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