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twk-18 TWiK family of potassium channels protein 18 [ Caenorhabditis elegans ]

Gene ID: 181139, updated on 2-Nov-2024

Summary

Official Symbol
twk-18
Official Full Name
TWiK family of potassium channels protein 18
Primary source
WormBase:WBGene00006672
Locus tag
CELE_C24A3.6
See related
AllianceGenome:WB:WBGene00006672
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables outward rectifier potassium channel activity. Involved in locomotion; muscle contraction; and potassium ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in body wall musculature. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See twk-18 in Genome Data Viewer
Location:
chromosome: X
Exon count:
8
Sequence:
Chromosome: X; NC_003284.9 (8988137..8991975)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene Alpha-methylacyl-CoA racemase Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables outward rectifier potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables outward rectifier potassium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IC
Inferred by Curator
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
TWiK family of potassium channels protein 18
NP_001379714.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    8988137..8991975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392816.1NP_001379714.1  TWiK family of potassium channels protein 18 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18120, Q9TZP8
    Conserved Domains (1) summary
    pfam07885
    Location:114170
    Ion_trans_2; Ion channel