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F49E2.5 Nucleolar protein 16;Translation initiation factor IF-2 [ Caenorhabditis elegans ]

Gene ID: 181175, updated on 2-Nov-2024

Summary

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Official Symbol
F49E2.5
Official Full Name
Nucleolar protein 16;Translation initiation factor IF-2
Primary source
WormBase:WBGene00009888
Locus tag
CELE_F49E2.5
See related
AllianceGenome:WB:WBGene00009888
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Is expressed in hypodermis; muscle cell; and neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F49E2.5 in Genome Data Viewer
Location:
chromosome: X
Exon count:
22
Sequence:
Chromosome: X; NC_003284.9 (9543652..9560804)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Deoxyribonuclease-2 Neighboring gene tRNA-Val Neighboring gene GTP 3',8-cyclase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
  2. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Crawford ED, et al. Cell Death Differ, 2012 Dec. PMID 22918439, Free PMC Article
  3. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  4. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nucleolar protein 16;Translation initiation factor IF-2
NP_001024694.1
  • Confirmed by transcript evidence
NP_001024695.1
  • Confirmed by transcript evidence
NP_001360758.1
  • Confirmed by transcript evidence
NP_001360760.1
  • Confirmed by transcript evidence
NP_001360761.1
  • Confirmed by transcript evidence
NP_001366700.1
  • Confirmed by transcript evidence
NP_001366701.1
  • Confirmed by transcript evidence
NP_001366703.1
  • Confirmed by transcript evidence
NP_001366704.1
  • Confirmed by transcript evidence
NP_001367019.1
  • Confirmed by transcript evidence
NP_001367097.1
  • Confirmed by transcript evidence
NP_001367224.1
  • Confirmed by transcript evidence
NP_001368747.1
  • Confirmed by transcript evidence
NP_001368748.1
  • Confirmed by transcript evidence
NP_001368749.1
  • Confirmed by transcript evidence
NP_001368750.1
  • Confirmed by transcript evidence
NP_001368751.1
  • Confirmed by transcript evidence
NP_001368752.1
  • Confirmed by transcript evidence
NP_001368753.1
  • Confirmed by transcript evidence
NP_001368754.1
  • Confirmed by transcript evidence
NP_001368755.1
  • Confirmed by transcript evidence
NP_001379062.1
  • Confirmed by transcript evidence
NP_001379063.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9543652..9560804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029524.6 → NP_001024695.1  Nucleolar protein 16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024695.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q565D1
    Conserved Domains (2) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612
    pfam09420
    Location:1018 → 1072
    Nop16; Ribosome biogenesis protein Nop16

  2. NM_001029523.6 → NP_001024694.1  Nucleolar protein 16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024694.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q565D2
    Conserved Domains (2) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612
    pfam09420
    Location:948 → 1002
    Nop16; Ribosome biogenesis protein Nop16

  3. NM_001373430.3 → NP_001360758.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKJ7
    Conserved Domains (2) summary
    PRK10811
    Location:834 → 996
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  4. NM_001392822.1 → NP_001379063.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20626
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  5. NM_001373432.4 → NP_001360760.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0ILU3
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  6. NM_001381054.2 → NP_001368747.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IJD5
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  7. NM_001381066.1 → NP_001368755.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IJF1
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 327
    DUF612; Protein of unknown function, DUF612

  8. NM_001381064.1 → NP_001366704.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20625
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 544
    DUF612; Protein of unknown function, DUF612

  9. NM_001381061.2 → NP_001368751.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0INR9
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 614
    DUF612; Protein of unknown function, DUF612

  10. NM_001373433.3 → NP_001360761.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IM76
    Conserved Domains (2) summary
    PRK10811
    Location:579 → 770
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  11. NM_001381055.1 → NP_001366703.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45544
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 486
    DUF612; Protein of unknown function, DUF612

  12. NM_001381056.1 → NP_001366700.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45541
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 627
    DUF612; Protein of unknown function, DUF612

  13. NM_001381057.1 → NP_001367097.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6BEV6
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 442
    DUF612; Protein of unknown function, DUF612

  14. NM_001381058.1 → NP_001368748.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKI2
    Conserved Domains (2) summary
    PRK10811
    Location:751 → 913
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 407
    DUF612; Protein of unknown function, DUF612

  15. NM_001381059.1 → NP_001368749.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKE7
    Conserved Domains (2) summary
    PRK10811
    Location:458 → 657
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 407
    DUF612; Protein of unknown function, DUF612

  16. NM_001381060.1 → NP_001368750.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKZ1
    Conserved Domains (2) summary
    PRK10811
    Location:566 → 757
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 592
    DUF612; Protein of unknown function, DUF612

  17. NM_001381062.1 → NP_001368752.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0INJ4
    Conserved Domains (2) summary
    PRK10811
    Location:496 → 687
    rne; ribonuclease E; Reviewed
    pfam04747
    Location:1 → 522
    DUF612; Protein of unknown function, DUF612

  18. NM_001381063.1 → NP_001368753.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V6M3D2
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 544
    DUF612; Protein of unknown function, DUF612

  19. NM_001381065.1 → NP_001368754.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKK7
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 327
    DUF612; Protein of unknown function, DUF612

  20. NM_001381067.1 → NP_001367224.1  Nucleolar protein 16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0VWM5
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 444
    DUF612; Protein of unknown function, DUF612

  21. NM_001392823.1 → NP_001379062.1  Translation initiation factor IF-2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45543
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612

  22. NM_001381069.1 → NP_001367019.1  Translation initiation factor IF-2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I4I3
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 407
    DUF612; Protein of unknown function, DUF612

  23. NM_001381070.1 → NP_001366701.1  Translation initiation factor IF-2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45542
    Conserved Domains (1) summary
    pfam04747
    Location:1 → 504
    DUF612; Protein of unknown function, DUF612
Nucleotide Protein
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