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C11E4.6 ANK_REP_REGION domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181179, updated on 2-Nov-2024

Summary

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Official Symbol
C11E4.6
Official Full Name
ANK_REP_REGION domain-containing protein
Primary source
WormBase:WBGene00007520
Locus tag
CELE_C11E4.6
See related
AllianceGenome:WB:WBGene00007520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in neurons. Orthologous to human ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) and ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C11E4.6 in Genome Data Viewer
Location:
chromosome: X
Exon count:
15
Sequence:
Chromosome: X; NC_003284.9 (9610563..9617045)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PID domain-containing protein Neighboring gene Neuropeptide-Like Protein;Organic solute transporter alpha-like protein;Transmembrane protein Neighboring gene tRNA-Ala

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
  2. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
  3. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
  4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
ANK_REP_REGION domain-containing protein
NP_509620.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9610563..9617045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077219.6 → NP_509620.2  ANK_REP_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509620.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93203
    Conserved Domains (6) summary
    smart00454
    Location:833 → 901
    SAM; Sterile alpha motif
    cd00204
    Location:55 → 186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00536
    Location:907 → 965
    SAM_1; SAM domain (Sterile alpha motif)
    pfam12796
    Location:66 → 164
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:135 → 164
    ANK; ANK repeat [structural motif]
    cl17171
    Location:1007 → 1151
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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