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col-176 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181219, updated on 2-Nov-2024

Summary

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Official Symbol
col-176
Official Full Name
Nematode cuticle collagen N-terminal domain-containing protein
Primary source
WormBase:WBGene00000749
Locus tag
CELE_ZC373.7
See related
AllianceGenome:WB:WBGene00000749
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See col-176 in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Sequence:
Chromosome: X; NC_003284.9 (10077597..10078728)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene putative methylthioribulose-1-phosphate dehydratase Neighboring gene Protein dao-4 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Further Extension of Lifespan by Unc-43/CaMKII and Egl-8/PLCβ Mutations in Germline-Deficient Caenorhabditis elegans. Mack HID, et al. Cells, 2022 Nov 8. PMID 36428956, Free PMC Article
  2. Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. Kroetz MB, et al. G3 (Bethesda), 2015 Oct 23. PMID 26497144, Free PMC Article
  3. Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model. Harr JC, et al. Genes Dev, 2020 Apr 1. PMID 32139421, Free PMC Article
  4. Ketamine induces apical extracellular matrix modifications in Caenorhabditis elegans. Yücel D. Sci Rep, 2022 Dec 21. PMID 36543791, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nematode cuticle collagen N-terminal domain-containing protein
NP_509692.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10077597..10078728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077291.7 → NP_509692.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509692.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23263
    Conserved Domains (2) summary
    pfam01391
    Location:150 → 190
    Collagen; Collagen triple helix repeat (20 copies)
    smart01088
    Location:6 → 58
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
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