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W07E11.1 glutamate synthase (NADH) [ Caenorhabditis elegans ]

Gene ID: 181223, updated on 2-Nov-2024

Summary

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Official Symbol
W07E11.1
Official Full Name
glutamate synthase (NADH)
Primary source
WormBase:WBGene00012326
Locus tag
CELE_W07E11.1
See related
AllianceGenome:WB:WBGene00012326
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glutamate synthase (NADH) activity. Predicted to be involved in ammonia assimilation cycle and glutamate biosynthetic process. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See W07E11.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
19
Sequence:
Chromosome: X; NC_003284.9 (10084622..10104650)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FMRF-Like Peptide Neighboring gene TPLGTMRF-amide Neighboring gene SPREPIRF-amide Neighboring gene ncRNA Neighboring gene Potassium channel domain-containing protein;Uncoordinated protein 58 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 3 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables FMN binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables glutamate synthase (NADH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutamate synthase (NADH) activity IEA
Inferred from Electronic Annotation
more info
  
enables glutamate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-NH2 group of donors IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-glutamate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ammonia assimilation cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutamate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutamate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamate synthase (NADH)
NP_001263967.1
  • Confirmed by transcript evidence
NP_001369873.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10084622..10104650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383634.1 → NP_001369873.1  glutamate synthase (NADH) [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EF05
    Conserved Domains (3) summary
    PRK11750
    Location:15 → 1511
    gltB; glutamate synthase subunit alpha; Provisional
    PRK12810
    Location:1671 → 2158
    gltD; glutamate synthase subunit beta; Reviewed
    pfam17380
    Location:1505 → 1690
    DUF5401; Family of unknown function (DUF5401)

  2. NM_001277038.5 → NP_001263967.1  glutamate synthase (NADH) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263967.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    K8F7V7
    Conserved Domains (3) summary
    PRK11750
    Location:15 → 1521
    gltB; glutamate synthase subunit alpha; Provisional
    PRK12810
    Location:1681 → 2168
    gltD; glutamate synthase subunit beta; Reviewed
    pfam17380
    Location:1515 → 1700
    DUF5401; Family of unknown function (DUF5401)
Nucleotide Protein
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