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nucb-1 NUCleoBindin homolog [ Caenorhabditis elegans ]

Gene ID: 181230, updated on 2-Nov-2024

Summary

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Official Symbol
nucb-1
Official Full Name
NUCleoBindin homolog
Primary source
WormBase:WBGene00009674
Locus tag
CELE_F44A6.1
See related
AllianceGenome:WB:WBGene00009674
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Predicted to be located in Golgi apparatus. Predicted to be active in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in body wall musculature; intestinal cell; neurons; and non-striated muscle. Orthologous to human NUCB1 (nucleobindin 1) and NUCB2 (nucleobindin 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nucb-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
9
Sequence:
Chromosome: X; NC_003284.9 (10197706..10200375)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Myelin regulatory factor homolog 2, N-terminal Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Steroid hormone receptor family member cnr14 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteins interacting with Caenorhabditis elegans Galpha subunits. Cuppen E, et al. Comp Funct Genomics, 2003. PMID 18629017, Free PMC Article
  2. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
  3. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NUCleoBindin homolog
NP_741885.1
  • Product from WormBase gene class nucb;
    Confirmed by transcript evidence
NP_741886.1
  • Product from WormBase gene class nucb;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10197706..10200375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171970.8 → NP_741886.1  NUCleoBindin homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741886.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20384, Q86RT3
    Conserved Domains (1) summary
    pfam13499
    Location:259 → 331
    EF-hand_7; EF-hand domain pair

  2. NM_171763.5 → NP_741885.1  NUCleoBindin homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741885.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86RT3, Q8MQ51
    Conserved Domains (1) summary
    pfam13499
    Location:259 → 331
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
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