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nas-10 Zinc metalloproteinase nas-10 [ Caenorhabditis elegans ]

Gene ID: 181287, updated on 2-Nov-2024

Summary

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Official Symbol
nas-10
Official Full Name
Zinc metalloproteinase nas-10
Primary source
WormBase:WBGene00003529
Locus tag
CELE_K09C8.3
See related
AllianceGenome:WB:WBGene00003529
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nas-10 in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (10960914..10963503, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Na(+)/H(+) exchanger protein 7 Neighboring gene Neuropeptide-Like Protein Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene tRNA-Gly Neighboring gene Glycosyltransferase-like protein LARGE Neighboring gene Secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans. Suzuki M, et al. Biol Chem, 2004 Jun. PMID 15255192
  2. The astacin protein family in Caenorhabditis elegans. Möhrlen F, et al. Eur J Biochem, 2003 Dec. PMID 14653817
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metalloendopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zinc metalloproteinase nas-10
NP_001257126.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10960914..10963503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270197.4 → NP_001257126.1  Zinc metalloproteinase nas-10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257126.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B6EU59, Q21388
    Conserved Domains (2) summary
    pfam01400
    Location:303 → 501
    Astacin; Astacin (Peptidase family M12A)
    pfam01549
    Location:503 → 540
    ShK; ShK domain-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q21388.2

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