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ver-3 Tyrosine-protein kinase receptor ver-3 [ Caenorhabditis elegans ]

Gene ID: 181289, updated on 2-Nov-2024

Summary

Official Symbol
ver-3
Official Full Name
Tyrosine-protein kinase receptor ver-3
Primary source
WormBase:WBGene00006896
Locus tag
CELE_F59F3.1
See related
AllianceGenome:WB:WBGene00006896
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in nematode male tail tip morphogenesis. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in ALA; anal sphincter muscle; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; bronchopulmonary dysplasia; diabetic retinopathy; and pre-eclampsia. Orthologous to human FLT1 (fms related receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ver-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
14
Sequence:
Chromosome: X; NC_003284.9 (10992477..10997851)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein kinase receptor ver-4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Potassium channel tetramerization-type BTB domain-containing protein Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nematode male tail tip morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Tyrosine-protein kinase receptor ver-3
NP_509836.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10992477..10997851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077435.7NP_509836.1  Tyrosine-protein kinase receptor ver-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509836.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21038
    Conserved Domains (7) summary
    smart00408
    Location:692747
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:8471163
    STYKc; Protein kinase; unclassified specificity
    smart00409
    Location:242313
    IG; Immunoglobulin
    smart00410
    Location:578667
    IG_like; Immunoglobulin like
    pfam07679
    Location:673757
    I-set; Immunoglobulin I-set domain
    cd00192
    Location:8511164
    PTKc; Catalytic domain of Protein Tyrosine Kinases
    pfam13927
    Location:578654
    Ig_3; Immunoglobulin domain