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mob-2 Mps One Binder (Mats/MOB1) homolog;Mps one binder kinase activator-like 2 [ Caenorhabditis elegans ]

Gene ID: 181441, updated on 2-Nov-2024

Summary

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Official Symbol
mob-2
Official Full Name
Mps One Binder (Mats/MOB1) homolog;Mps one binder kinase activator-like 2
Primary source
WormBase:WBGene00008601
Locus tag
CELE_F09A5.4
See related
AllianceGenome:WB:WBGene00008601
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB2 (MOB kinase activator 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mob-2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (13152820..13170075, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene Coexpressed With Polycystins

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. Gruneberg U, et al. J Cell Biol, 2002 Sep 2. PMID 12213836, Free PMC Article
  2. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Mps One Binder (Mats/MOB1) homolog;Mps one binder kinase activator-like 2
NP_001257214.1
  • Confirmed by transcript evidence
NP_001379308.1
  • Confirmed by transcript evidence
NP_510184.1
  • Confirmed by transcript evidence
NP_510185.1
  • Confirmed by transcript evidence
NP_510186.1
  • Confirmed by transcript evidence
NP_741916.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13152820..13170075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077783.5 → NP_510184.1  Mps one binder kinase activator-like 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510184.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECT9
    Conserved Domains (1) summary
    pfam03637
    Location:120 → 287
    Mob1_phocein; Mob1/phocein family

  2. NM_077784.7 → NP_510185.1  Mps One Binder (Mats/MOB1) homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19237
    Conserved Domains (1) summary
    pfam03637
    Location:70 → 237
    Mob1_phocein; Mob1/phocein family

  3. NM_077785.5 → NP_510186.1  Mps one binder kinase activator-like 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510186.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JLW3
    Conserved Domains (1) summary
    pfam03637
    Location:111 → 278
    Mob1_phocein; Mob1/phocein family

  4. NM_001392870.1 → NP_001379308.1  Mps one binder kinase activator-like 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQ84
    Conserved Domains (1) summary
    pfam03637
    Location:94 → 261
    Mob1_phocein; Mob1/phocein family

  5. NM_171789.6 → NP_741916.1  Mps one binder kinase activator-like 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741916.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQ85
    Conserved Domains (1) summary
    pfam03637
    Location:84 → 251
    Mob1_phocein; Mob1/phocein family

  6. NM_001270285.4 → NP_001257214.1  Mps One Binder (Mats/MOB1) homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257214.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GUA6
    Conserved Domains (1) summary
    pfam03637
    Location:25 → 192
    Mob1_phocein; Mob1/phocein family

RNA

  1. NR_002420.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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