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fkh-3 Forkhead box protein fkh-3 [ Caenorhabditis elegans ]

Gene ID: 181465, updated on 2-Nov-2024

Summary

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Official Symbol
fkh-3
Official Full Name
Forkhead box protein fkh-3
Primary source
WormBase:WBGene00001435
Locus tag
CELE_C29F7.4
See related
AllianceGenome:WB:WBGene00001435
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fkh-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
3
Sequence:
Chromosome: X; NC_003284.9 (13421822..13423440, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CHK kinase-like domain-containing protein Neighboring gene UMP-CMP kinase 1 Neighboring gene Forkhead box protein fkh-4 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Promoters recognized by forkhead proteins exist for individual 21U-RNAs. Cecere G, et al. Mol Cell, 2012 Sep 14. PMID 22819322, Free PMC Article
  2. The forkhead gene family of Caenorhabditis elegans. Hope IA, et al. Gene, 2003 Jan 30. PMID 12568714
  3. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Panowski SH, et al. Nature, 2007 May 31. PMID 17476212
  4. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
  5. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Forkhead box protein fkh-3
NP_001294822.1
  • Confirmed by transcript evidence
NP_001294823.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13421822..13423440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307893.4 → NP_001294822.1  Forkhead box protein fkh-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294822.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A078BQN7, A0A078BTN3
    Conserved Domains (1) summary
    smart00339
    Location:118 → 206
    FH; FORKHEAD

  2. NM_001307894.4 → NP_001294823.1  Forkhead box protein fkh-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294823.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BTN3
    Conserved Domains (2) summary
    smart00339
    Location:93 → 181
    FH; FORKHEAD
    COG5025
    Location:13 → 169
    COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
Nucleotide Protein
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