U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hlb-1 Liprin-beta homolog [ Caenorhabditis elegans ]

Gene ID: 181499, updated on 2-Nov-2024

Summary

Official Symbol
hlb-1
Official Full Name
Liprin-beta homolog
Primary source
WormBase:WBGene00011904
Locus tag
CELE_T21H8.1
See related
AllianceGenome:WB:WBGene00011904
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in neuromuscular junction development; positive regulation of locomotion; and regulation of nematode pharyngeal pumping. Predicted to be active in presynaptic active zone. Orthologous to human PPFIBP1 (PPFIA binding protein 1) and PPFIBP2 (PPFIA binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See hlb-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
20
Sequence:
Chromosome: X; NC_003284.9 (13865033..13882739, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Liprin-beta homolog
NP_001123185.1
  • Partially confirmed by transcript evidence
NP_001309703.1
  • Partially confirmed by transcript evidence
NP_001309704.1
  • Partially confirmed by transcript evidence
NP_001309705.1
  • Confirmed by transcript evidence
NP_001309706.1
  • Partially confirmed by transcript evidence
NP_001309707.1
  • Confirmed by transcript evidence
NP_001309708.1
  • Partially confirmed by transcript evidence
NP_001309709.1
  • Confirmed by transcript evidence
NP_001309710.1
  • Partially confirmed by transcript evidence
NP_001309713.1
  • Confirmed by transcript evidence
NP_001309714.1
  • Partially confirmed by transcript evidence
NP_001309716.1
  • Confirmed by transcript evidence
NP_001309717.1
  • Confirmed by transcript evidence
NP_001309718.1
  • Partially confirmed by transcript evidence
NP_001364846.1
  • Partially confirmed by transcript evidence
NP_001379172.1
  • Confirmed by transcript evidence
NP_001380196.1
  • Confirmed by transcript evidence
NP_001380197.1
  • Confirmed by transcript evidence
NP_510311.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13865033..13882739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001322656.4NP_001309704.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBV4
    Conserved Domains (3) summary
    cd09563
    Location:606669
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:680742
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:768839
    SAM_superfamily; SAM (Sterile alpha motif )
  2. NM_001322647.4NP_001309707.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MD98
    Conserved Domains (4) summary
    cd09563
    Location:653716
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:727789
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:815886
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    COG1196
    Location:216427
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. NM_001322660.3NP_001309706.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MD42
    Conserved Domains (3) summary
    cd09563
    Location:374437
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:448510
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:536607
    SAM_superfamily; SAM (Sterile alpha motif )
  4. NM_001322649.4NP_001309709.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBE2
    Conserved Domains (4) summary
    cd09563
    Location:627690
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:701763
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:789860
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    COG1196
    Location:190401
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  5. NM_001322650.3NP_001309710.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBC5
    Conserved Domains (4) summary
    cd09563
    Location:669732
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:743805
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:190401
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:831902
    SAM_superfamily; SAM (Sterile alpha motif )
  6. NM_077910.5NP_510311.2  Liprin-beta homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510311.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94071
    Conserved Domains (4) summary
    cd09563
    Location:611674
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:685747
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:174385
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:773844
    SAM_superfamily; SAM (Sterile alpha motif )
  7. NM_001129713.4NP_001123185.1  Liprin-beta homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001123185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A7LPI2
    Conserved Domains (4) summary
    cd09563
    Location:653716
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:727789
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:174385
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:815886
    SAM_superfamily; SAM (Sterile alpha motif )
  8. NM_001322648.4NP_001309708.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A131MBC5, A0A131MBE2, A0A131MBV4, A0A131MBW2, A0A131MBW4, A0A131MBY3, A0A131MBZ3, A0A131MC19, A0A131MC32, A0A131MCT0, A0A131MD42, A0A131MD54, A0A131MD98, A0A131MDA8, A0A131MDI4, A0A131MDJ4, A7LPI2, Q94071, Q94075
    Conserved Domains (4) summary
    cd09563
    Location:695758
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:769831
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:857928
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    COG1196
    Location:216427
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  9. NM_001392878.1NP_001380196.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (4) summary
    cd09563
    Location:561624
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:635697
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:124335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:723794
    SAM_superfamily; SAM (Sterile alpha motif )
  10. NM_001377622.2NP_001364846.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (4) summary
    cd09563
    Location:603666
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:677739
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:124335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:765836
    SAM_superfamily; SAM (Sterile alpha motif )
  11. NM_001322653.5NP_001309713.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MDJ4
    Conserved Domains (4) summary
    cd09563
    Location:474537
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:548610
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:37248
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:636707
    SAM_superfamily; SAM (Sterile alpha motif )
  12. NM_001322654.3NP_001309714.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBW2
    Conserved Domains (4) summary
    cd09563
    Location:516579
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:590652
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:37248
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:678749
    SAM_superfamily; SAM (Sterile alpha motif )
  13. NM_001322655.3NP_001309703.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MDI4
    Conserved Domains (3) summary
    cd09563
    Location:564627
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:638700
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:726797
    SAM_superfamily; SAM (Sterile alpha motif )
  14. NM_001322657.3NP_001309717.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MDA8
    Conserved Domains (4) summary
    cd09563
    Location:462525
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:536598
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:25236
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:624695
    SAM_superfamily; SAM (Sterile alpha motif )
  15. NM_001322658.3NP_001309718.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBZ3
    Conserved Domains (4) summary
    cd09563
    Location:504567
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:578640
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    COG1196
    Location:25236
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl15755
    Location:666737
    SAM_superfamily; SAM (Sterile alpha motif )
  16. NM_001322659.3NP_001309705.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MC19
    Conserved Domains (3) summary
    cd09563
    Location:332395
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:406468
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:494565
    SAM_superfamily; SAM (Sterile alpha motif )
  17. NM_001392879.1NP_001380197.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

  18. NM_001392880.1NP_001379172.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

  19. NM_001322662.1NP_001309716.1  Liprin-beta homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MD54