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serp-1.1 Stress-associated endoplasmic reticulum protein 2 [ Caenorhabditis elegans ]

Gene ID: 181669, updated on 2-Nov-2024

Summary

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Official Symbol
serp-1.1
Official Full Name
Stress-associated endoplasmic reticulum protein 2
Primary source
WormBase:WBGene00010337
Locus tag
CELE_F59F4.2
See related
AllianceGenome:WB:WBGene00010337
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in body wall musculature; intestine; nervous system; pharynx; and seam cell. Orthologous to human SERP1 (stress associated endoplasmic reticulum protein 1) and SERP2 (stress associated endoplasmic reticulum protein family member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See serp-1.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Sequence:
Chromosome: X; NC_003284.9 (15841572..15842379)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Acyl-coenzyme A oxidase Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1 Neighboring gene DNA repair and recombination protein RAD54-like Neighboring gene DUF19 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternative redox forms of ASNA-1 separate insulin signaling from tail-anchored protein targeting and cisplatin resistance in C. elegans. Raj D, et al. Sci Rep, 2021 Apr 21. PMID 33883621, Free PMC Article
  2. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
  3. The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity. Bailly AP, et al. Cell Rep, 2019 Oct 1. PMID 31577950, Free PMC Article
  4. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
  5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to unfolded protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Stress-associated endoplasmic reticulum protein 2
NP_001379193.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    15841572..15842379
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392905.1 → NP_001379193.1  Stress-associated endoplasmic reticulum protein 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93838
    Conserved Domains (1) summary
    pfam06624
    Location:2 → 58
    RAMP4; Ribosome associated membrane protein RAMP4
Nucleotide Protein
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