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cah-3 Putative carbonic anhydrase 3 [ Caenorhabditis elegans ]

Gene ID: 181713, updated on 2-Nov-2024

Summary

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Official Symbol
cah-3
Official Full Name
Putative carbonic anhydrase 3
Primary source
WormBase:WBGene00000281
Locus tag
CELE_K05G3.3
See related
AllianceGenome:WB:WBGene00000281
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be active in cytoplasm. Is expressed in several structures, including intestine; pharynx; somatic cell; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA14 (carbonic anhydrase 14) and CA4 (carbonic anhydrase 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cah-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (16487481..16489397)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene 3'-5' exonuclease domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a nuclear carbonic anhydrase in Caenorhabditis elegans. Sherman TA, et al. Biochim Biophys Acta, 2012 Apr. PMID 22245567, Free PMC Article
  2. Molecular and biochemical analysis of the α class carbonic anhydrases in Caenorhabditis elegans. Fasseas MK, et al. Mol Biol Rep, 2011 Mar. PMID 20842438
  3. Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. Mathew ND, et al. J Toxicol, 2011. PMID 22131987, Free PMC Article
  4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Putative carbonic anhydrase 3
NP_001370788.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    16487481..16489397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383694.2 → NP_001370788.1  Putative carbonic anhydrase 3 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q27504
    Conserved Domains (1) summary
    smart01057
    Location:5 → 239
    Carb_anhydrase; Eukaryotic-type carbonic anhydrase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27504.1

Gene LinkOut

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