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abu-1 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

Gene ID: 181800, updated on 2-Nov-2024

Summary

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Official Symbol
abu-1
Official Full Name
Activated in Blocked Unfolded protein response
Primary source
WormBase:WBGene00000024
Locus tag
CELE_AC3.3
See related
AllianceGenome:WB:WBGene00000024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in endoplasmic reticulum unfolded protein response. Located in endoplasmic reticulum membrane. Is expressed in pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See abu-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
2
Sequence:
Chromosome: V; NC_003283.11 (10380340..10381826, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Activin types I and II receptor domain-containing protein;Activin_recp domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Palmitoyltransferase spe-10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
  2. Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Sun J, et al. Science, 2011 May 6. PMID 21474712, Free PMC Article
  3. Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Haskins KA, et al. Dev Cell, 2008 Jul. PMID 18606143, Free PMC Article
  4. Regulated trafficking of the MSP/Eph receptor during oocyte meiotic maturation in C. elegans. Cheng H, et al. Curr Biol, 2008 May 20. PMID 18472420, Free PMC Article
  5. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. Urano F, et al. J Cell Biol, 2002 Aug 19. PMID 12186849, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
involved_in endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Activated in Blocked Unfolded protein response
NP_505667.1
  • Product from WormBase gene class abu;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10380340..10381826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073266.4 → NP_505667.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505667.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17400
    Conserved Domains (1) summary
    pfam06493
    Location:19 → 69
    DUF1096; Protein of unknown function (DUF1096)
Nucleotide Protein
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