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pitr-3 Phosphate transporter [ Caenorhabditis elegans ]

Gene ID: 181858, updated on 2-Nov-2024

Summary

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Official Symbol
pitr-3
Official Full Name
Phosphate transporter
Primary source
WormBase:WBGene00015055
Locus tag
CELE_B0222.3
See related
AllianceGenome:WB:WBGene00015055
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Is expressed in hypodermis; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pitr-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (9138946..9141397, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Phosphate transporter Neighboring gene ncRNA Neighboring gene Sphingosine Phosphate Lyase Neighboring gene BPTI/Kunitz inhibitor domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes. Hellwig S, et al. Proc Natl Acad Sci U S A, 2008 Sep 2. PMID 18723671, Free PMC Article
  2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphate ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Phosphate transporter
NP_505371.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9138946..9141397 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072970.6 → NP_505371.2  Phosphate transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505371.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17455
    Conserved Domains (2) summary
    COG0306
    Location:31 → 490
    PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
    pfam01384
    Location:383 → 481
    PHO4; Phosphate transporter family
Nucleotide Protein
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